Gold just a useless commodity?

Saturday, August 9, 2008

I think we have missed out on some of the uses of precious metals which seem to be making a resurgence after thousands of years.

It is well known to the moderately intelligent Indian who has not fully migrated to McDonalds and Bling, that water kept silver vessels will kill bacteria. A recent application of silver has been in Air handling units where it is used to neutralise bacteria in the air stream.

It's the same case for gold. Early uses apart from the use of jewelery (which btw, was not merely for decorative purposes, but the heavy gold jewelery adorning the bare chests of men ensured absorption of gold molecules which serve a healthy purpose), also included the use of gold for false teeth on account of it's malleability, ductility and it's inertness.

Gold is now used in the manufacture of integrated circuits on account of it's ductility, non-corrosiveness and high conductivity.

Recent research has been going on in the use of gold in the manufacture of DNA sensors which would be used to detect diseases.

I dare say that the future will see more and more applications of this beautiful metal.

Excerpts from recent research:

ScienceDaily (Aug. 23, 1997) — Evanston, Ill. --- Researchers at Northwestern University have combined gold and DNA in an innovative way that should lead to new techniques for detecting many types of diseases. Screening for genetic and pathogenic diseases -- that is, those transmitted through heredity and those transmitted by microorganisms -- may be done using the new material, according to one of its inventors, Chad A. Mirkin, professor of chemistry at Northwestern.

Functionalized nanoparticles are covalently bound to internal, chemically modified bases on double-stranded DNA without the presence of destabilizing "nicks" along the DNA backbone. In addition, we report an approach for thiolating one end of the DNA/nanoparticle product and attaching it to a gold surface. The ability to attach one or both ends of the DNA/gold complex, after generation of the desired pattern, to fixed contacts or electrodes is necessary for nanodevices fabrication.

Abstract. This report presents the use of disulfide-modified single-stranded DNA (ssDNA) to form DNA self-assembled monolayers (SAMs) and mixed DNA-carbon nanotube (CNT) hybrids SAMs on gold substrates. Mixed DNA-CNT SAMs are composed of DNA,
mercaptohexanol (MCH) and DNA-CNT aggregates. Both, DNA-CNT and DNA areas of the mixed SAMs were analyzed and compared to traditional DNA SAMs. The results suggest the formation of a more compact and densely packed monolayer of DNA-CNT in comparison with DNA. The use of DNA-CNT hybrids to form SAMs on gold substrates might represent a new approach to improve the immobilization of DNA strands on gold, and might therefore help with the development of enhanced DNA sensors.

Posted by Pithaly at 11:13 PM  

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